The role of male factors in possible recurrent implantation failure: a case report.

Male factors and recurrent implantation failure.

Abstract

Introduction: Recurrent implantation failure (RIF) poses a significant challenge in in vitro fertilization (IVF) procedures. Although maternal factors are often considered, the role of male factors, particularly sperm quality, remains under investigation.

Material and Methods: This case report aims to evaluate the potential relationship between male factors and recurrent implantation failure in IVF.

Results: We present the case of a 33-year-old male partner of a couple experiencing RIF in IVF who underwent semen analysis and additional functional tests to assess sperm quality. Despite normal conventional semen analysis parameters, functional tests revealed abnormalities, including high levels of DNA fragmentation, low percentage in the hypoosmotic test, and low concentrations of inorganic phosphorus.

Conclusions: The identification of functional sperm alterations underscores the importance of tailored approaches to address male infertility and improve the success rates of assisted reproductive technologies.