Prescription of Antibiotics in Bone Augmentation with Dental Implant

Antibiotics Effect on Dental Implant with Bone Augmentation

Abstract

Aim: To evaluate the success and failure in bone augmentation with dental implant cases when antibiotics used with different timing in long follow up periods.

Material and Method: 120 patients were randomly allocated to 3 different categories: (1) no antibiotic treatment (NOAB), (2) preoperative and postoperative antibiotic treatment (PPAB) consisting of amoxicillin 1.5 g 1 hour before surgery and 500 mg three times per day; for 5 days following surgery, (3) postoperative antibiotic coverage (POAB) consisting of and 500 mg three times per day; started after surgery and continued for 5 days after surgery. Comparison and follow-up of patients to detect response to antibiotics in case of bone augmentation and dental implant.

Results: High significant differences recorded in age groups and gender. In the third day, 12^th week and after six months follow-up shows high significant differences subsequently ( 0.000, 0.000 and 0.041). Failure seen in group (1 and 3) were from group one ( 7 implants / 11.6%)  are failed while in group three just only (2 implants / 3.33%)  are failed on the contrary in group two all implants are succeed (100%).

Conclusion: The use of preventive antibiotics results in a very low infection rate. Conversely, the absence of preventive antibiotics significantly increased the infection rate. A greater number of studies are required to analyze the biological factors that contribute to failure in the case of various antibiotic doses and kinds.