Development of a low-grade glioma in an ischemic brain territory that evolved into a glioblastoma. A case report and brief literature review.

Abstract

Abstract

Introduction: Glioblastoma is one of the most common and aggressive brain tumours with a very high mortality rate. It often evolves from a late or misdiagnosed astrocytoma. Stroke is one of the most common pathologies of the brain, affecting approximately 1.1 million Europeans each year. This article presents the sequential development of a low-grade astrocytoma in an ischemic brain territory into a high-grade glioblastoma.

Case presentation: A 59-year-old patient presented to our hospital with vague neurological symptoms. Clinical findings and control imaging revealed the presence of an ischemic brain area with atypical imaging characteristics. Monthly brain magnetic resonance imaging (MRI) follow-up revealed the development of a low-grade astrocytoma in the ischemic territory, which later evolved into a glioblastoma.

Conclusions: Patients who suffer from an atypical stroke on imaging should be closely monitored via MRI to prevent the rare development of tumour pathology in the affected territory.